Peptide Database

Peptide NameTheta defensin subunit A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC353H571N101O106S6

DescriptionStandard

        MKTFALLTAMLLLVALHAQAEARQARADEAAAQEQPGADDQGMAPSFTWPESAALPLSESAKGLRCICTRGFCRLL
    

Molecular Weight8118.31 Da

Isoelectric Point (pI)5.66

Net Charge (pH 7.0)-1.43

Net Charge (pH 7.4) -1.75

Charge Density (pH 7.0) -0.0188

GRAVY Index0.09

Hydrophobic Moment 0.57

Boman Index0.08

Instability Index40.01

Aliphatic Index 86.45

Aromaticity 0.0526

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3292.36

LogP -33.55

H-bond Donors 116.0

H-bond Acceptors 112.0

Rotatable Bonds 266.0

Heavy Atoms 566.0

Ring Count 10.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0242145 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinopithecus roxellana [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Defensin Non-hemolytic Non-ribosomal