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MYP_038973
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Basic Information
Antimicrobial peptide, Maximin H2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Reproductive biology ▸ Contraceptive activity ▸ Spermicidal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
20 amino acids
C91H164N22O23S
Standard
Sequence
ILGPVLSMVGSALGGLIKKI
Physicochemical Analysis
1966.47 Da
10.00
1.76
1.55
0.0879
1.41
0.51
0.52
22.20
170.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
699.93
-3.71
24.0
26.0
67.0
137.0
1.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0169598 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Maximin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus ATCC 2592
2 μg/mL
MIC
PaperVariety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification. Eur J Immunol. 2005 Apr;35(4):1220-1229. doi: 10.1002/eji.200425615. PMID: 15770703. | Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima. Peptides. 2002 Mar;23(3):427-435. doi: 10.1016/S0196-9781(01)00641-6. PMID: 11835991. PMID15770703;11835991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15770703/
RECORD: Rec_0242320 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
161274
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli ATCC 25922
20 μg/mL
MIC
PaperAntimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
RECORD: Rec_0268962 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Maximin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans ATCC 2002
2 μg/mL
MIC
PaperVariety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification. Eur J Immunol. 2005 Apr;35(4):1220-1229. doi: 10.1002/eji.200425615. PMID: 15770703. | Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima. Peptides. 2002 Mar;23(3):427-435. doi: 10.1016/S0196-9781(01)00641-6. PMID: 11835991. PMID15770703;11835991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15770703/
RECORD: Rec_0288192 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Maximin H
161274
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Antiviral Anti-HIV-1 Spermicidal
PaperR. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima PMID11835991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11835991/
RECORD: Rec_0302853 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Maximin
161274
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
20 μg/mL
MIC
PMID11835991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11835991/
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