Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC590H958N168O184S8

DescriptionStandard

        MKLLLLALPILVLLPQVIPAYGGEKKCWNRSGHCRKQCKDGEAVKETCKNLRACCVPSNEDHRRLPTTSPTPLSDSTPGIIDNILTIRFTTDYFEISSKKDMVEESEAGQGTQTSPPNVHHTS
    

Molecular Weight13605.45 Da

Isoelectric Point (pI)7.62

Net Charge (pH 7.0)0.81

Net Charge (pH 7.4) 0.27

Charge Density (pH 7.0) 0.0066

GRAVY Index-0.47

Hydrophobic Moment 0.64

Boman Index-0.07

Instability Index60.04

Aliphatic Index 78.46

Aromaticity 0.0407

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5637.01

LogP -62.95

H-bond Donors 198.0

H-bond Acceptors 197.0

Rotatable Bonds 448.0

Heavy Atoms 950.0

Ring Count 20.0

Amide Bonds 131.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224237 VERIFIED: NO

Provenance & Taxonomy

OrganismCercocebus atys [Animal]

FamilyBeta-defensin; Defensin

Tax ID9531

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

RECORD: Rec_0386517 VERIFIED: NO