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MYP_038957
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Standard
16 amino acids
C104H167N33O19S
Standard
Sequence
RQIKIWFPNRRMKWKK
Physicochemical Analysis
2215.71 Da
12.00
6.76
6.55
0.4223
-1.61
0.30
-0.56
58.64
48.75
0.1875
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
898.57
-3.84
33.0
27.0
76.0
157.0
6.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0233246 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
Penetratin
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID8663410 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8663410/
RECORD: Rec_0262738 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Penetratin-derived peptide
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-HIV Anti-HSV Anti-Influenza Entry inhibitor
HSV-1
7 μM
IC50
PaperMethod of inhibiting influenza infection with antiviral peptides Evidence URLhttps://patents.google.com/patent/US7432045B2/en PatentUS 7432045 B2
RECORD: Rec_0336535 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
Penetratin
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
N-term detail: Labeled with fluorescein
Bio-Activity Profile
Cell-penetrating peptide
HaCat/ A549 cells
Fluorescence-based uptake assay
PMID10784032 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10784032/
RECORD: Rec_0424629 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
Penetratin
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
Amidation
N-term detail: Biotinylation
Bio-Activity Profile
Cell-penetrating peptide
Cortical striatal cells
Cellular uptake assay
PMID8663410 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8663410/
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