Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length439 amino acids

Chemical FormulaC2232H3500N588O618S9

DescriptionStandard

        HQHGIAILEKELAQLTLPDISGDFRVLRVGKVHYELSRLRLRNFHLPYSRISPVPNVGLQVSISNAFAELDGDWRVKMLFIRDHGSFDLKVENVYIKISLSLGSDAAGKPTISTSDCSTRISKVRVLFSGKFGWLYNLFHSAIESKFKKILESKVCDSVAKSVHSELQTYMRTLPVTAKIDARTGIDYSFVAPPVATAQSLDTGLKGEFYSLAHRSPAPFSPLPLSLPSDHDRMVYFGASSYFFNTAGFAYHSSGALVFEITDAKIPKDVDFHLNTSTFSAFVPQLEQMYPNMPMKLRLSTLTAPFLNIGPEGISLKPVVDVQAYAILPNSSLAPLFVLSLVRNVSAVIDVRSGHIVGSLNVGRIKLSLKDSVVGTFPVRLLQSIMNIFASEILLPRLNARLDEGFPLPLPDRIQLFNTFVRFHQNFLLLGADVHFQPK
    

Molecular Weight48747.82 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)8.99

Net Charge (pH 7.4) 7.96

Charge Density (pH 7.0) 0.0205

GRAVY Index0.11

Hydrophobic Moment 0.71

Boman Index0.12

Instability Index41.23

Aliphatic Index 102.35

Aromaticity 0.1002

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0394125 VERIFIED: NO

Provenance & Taxonomy

OrganismTyrannus savana (Fork-tailed flycatcher) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria