Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length443 amino acids

Chemical FormulaC2226H3536N596O619S12

DescriptionStandard

        AHQQGIAILEKELAQLKLPDISGDSRVLKVGKVHYELSRLRIPNFRLPYSRITPISNKGLQVSISNAFVELDGDWRVKFLFVRDHGSFNLKVENVYIKIILRLGSDTTGKPTISTSDCTAHISKVRVHFSGKFGYVTSLEGLETLCLCGLSVPQVCDNVAKSVQNELQKQIRTLPVTARIDDKTGIDYALVAAPRATAKSLDVYLKGEFYSLGHRSTVPFSPLPLAFPSDHDRMVYFGASSYFFNTAGIAYHKAGALVFEITEAMMPKNARFRLDTSVFSVFIPQLEEMYPNMPMKFRLSAPTAPFLTIGPGGISFQPIVDAQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGRIVGSLDVGRIRLSLKDSAVGTFQVQFLQSIMNFLTSNVLLPHLNARLDEGFPLPLLDRIQLSNIIVRFHQVSEGQHLVPAGPMLLPPK
    

Molecular Weight48936.29 Da

Isoelectric Point (pI)9.43

Net Charge (pH 7.0)11.75

Net Charge (pH 7.4) 10.86

Charge Density (pH 7.0) 0.0265

GRAVY Index0.12

Hydrophobic Moment 0.66

Boman Index0.11

Instability Index34.06

Aliphatic Index 104.06

Aromaticity 0.0880

Extinction Coeff. Reduced 23380.00

Extinction Coeff. Oxidized 23630.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0373818 VERIFIED: NO

Provenance & Taxonomy

OrganismCettia cetti [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria