Peptide Database

Peptide NamePutative colicin activity protein (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length328 amino acids

Chemical FormulaC1570H2549N479O488S7

DescriptionStandard

        MMSKIVTSLPAETVTNVQVSTLPLDQATVRVTKRVTDVVKDKRQHIAVVAGVPMSVPVVNAKPTRTPGVFRASFPGVPSLTLSTVKGLPASTTLPRGITEDKGRTASPAGFTFGGGSHEAVIRFPKESGQKPVYVSVTDVLTSAQVKQRQDEENRLQQEWNDTHPVEVAERNYEQARAELNQANKDVARNQERQAKAVHVYNSRKSELDAANKTFADAKAEIKRFERFAREPMAAGHRMWQMAGLKAQRAQTDVNNKKAAFDAAAKEKSAADAALSSAMESRKKKEDKKRSAENKLNEEKNKPRKGVKDYGHDYHPAPKTEEIKGWGN
    

Molecular Weight36167.41 Da

Isoelectric Point (pI)9.81

Net Charge (pH 7.0)16.16

Net Charge (pH 7.4) 15.48

Charge Density (pH 7.0) 0.0493

GRAVY Index-0.79

Hydrophobic Moment 0.90

Boman Index-0.19

Instability Index44.63

Aliphatic Index 63.69

Aromaticity 0.0518

Extinction Coeff. Reduced 23950.00

Extinction Coeff. Oxidized 23950.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078893 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyColicin/Bacteriocin

Tax ID585034

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence