Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length506 amino acids

Chemical FormulaC2519H3964N660O693S21

DescriptionStandard

        MAPHPPKPSGPISGHLWGCLLPPLPPLPRFLPPFYILLVSISPAGSFRAPWLPSKASRFGGSGRQNMAREPDKASMRATLVVLATLGTAVIATTNPGVVARITQKGLDYACQQGMTVLRKELEKITIPTFSGTFEIKHLGEGHYSFYSKTSGNFDLSVEGVSISAGLKPGFDPASGHCTVTCSACRNHIESVRVHISGSGLGWLIKLFHKKMESALQKMMNKKICQVVTNSVSSKLQPYLETLPVKTQIDNVAGIDYSLVAPPTTTTDNLDGQLKGEFFRWNQRSPPPFAPPPLAFPGDHDRMVYLGISDYFFNTAGFVYQQAGALNLTVTDNMIPKKSKFRLTTNFFGILIPQVATMFPNMEVQLVFWASSPPHLTMNPASLVFTPTLDTQAFAVLQNSSLAPLFVLRLTMNISVTVGATLDRLVGQLELNKLLLELKHSDVGPFSVGVLQAVMSYVVPIAVIPKVNERLQKGFPLPMPAKLQAFNLVLRSHQNFLLLGADVRYS
    

Molecular Weight55255.79 Da

Isoelectric Point (pI)9.53

Net Charge (pH 7.0)15.51

Net Charge (pH 7.4) 14.51

Charge Density (pH 7.0) 0.0306

GRAVY Index0.09

Hydrophobic Moment 0.65

Boman Index0.15

Instability Index44.35

Aliphatic Index 93.04

Aromaticity 0.0889

Extinction Coeff. Reduced 43890.00

Extinction Coeff. Oxidized 44265.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0405742 VERIFIED: NO

Provenance & Taxonomy

OrganismSuricata suricatta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria