Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length459 amino acids

Chemical FormulaC2311H3643N621O641S12

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQAIAFLEKELAQLKLPDISGDFRIRAVGKVRYEISRLDLQSFRLPYSRISLVPNVGLQVSISNAFAEVDGNWRVKVLFIRDHGSFDLKVDNVYIKINLKLGSDASGKPTIDTSDCSTSISSVRVHFSGRLGWLYNLFHHAIESRFRKILESKVCDSVARSVRGELQTYLRTLPVTARIDDRVGIDYSLVASPTATTQSLDTDLKGEFFSLAQRSAVPFPPLPLAFPPDHDRMVYFGASCYFFNTAAFAYHAARALVFDITGAMLFSPRNGGLSCCPYPLPAPLQLDKIYPEMPMKFRLSAPSAPLLNIGPEGLSLKPVVDIQAYAILPNSSLVPLFLLNVTSNVSAMIDVKSGHIVGSLKVGSHTLSCRLKLFSFPLAQVRPLQSIMNVVASSILLPRLNARLDEGFPLPLPDRIQLSNILVRFHQNFLLLGADVHFQPQ
    

Molecular Weight50767.20 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)9.33

Net Charge (pH 7.4) 8.41

Charge Density (pH 7.0) 0.0203

GRAVY Index0.13

Hydrophobic Moment 0.83

Boman Index0.11

Instability Index36.00

Aliphatic Index 104.29

Aromaticity 0.0937

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30745.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240420 VERIFIED: NO

Provenance & Taxonomy

OrganismTrogon melanurus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria