Peptide Database

Peptide Namegamma-gliadin 1375 (p61-p80; E64, E66, E69 and E76) ; gamma-gliadin M7 M36999 (p61-p80) homologous to DQ2-gamma-III

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC110H153N25O36

DescriptionStandard

        QFPETEQPEQPFPQPEQTFP
    

Molecular Weight2401.54 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-4.23

Net Charge (pH 7.4) -4.44

Charge Density (pH 7.0) -0.2114

GRAVY Index-1.71

Hydrophobic Moment 0.39

Boman Index-0.15

Instability Index153.53

Aliphatic Index 0.00

Aromaticity 0.1500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 968.59

LogP -9.08

H-bond Donors 26.0

H-bond Acceptors 32.0

Rotatable Bonds 68.0

Heavy Atoms 171.0

Ring Count 9.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0405721 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E64,E66,E69; Reported substitutions/positions: E76; Reported substitutions/positions: M7; Reported substitutions/positions: M36999

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay