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MYP_038819
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Basic Information
Urocortin III
Cardiovascular
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuropeptide activity ▸ Stress-related neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
38 amino acids
C185H306N52O51S2
Standard
Sequence
FTLSLDVPTNIMNLLFNIAKAKNLRAQAAANAHLMAQI
Physicochemical Analysis
4138.86 Da
9.99
1.85
1.59
0.0486
0.45
0.60
0.20
40.06
121.05
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1673.47
-15.31
55.0
56.0
138.0
290.0
4.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0038007 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; synthetic construct [Synthetic]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
RECORD: Rec_0078662 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Sauvagine/corticotropin-releasing factor/urotensin I
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Stress-related neuropeptide
RECORD: Rec_0154606 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Urocortin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Cardiovascular Metabolic regulation Physiological regulation Receptor modulation ACE inhibitory Feeding regulator
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Urocortin-3 (Homo sapiens): PMID 11416224 PMID11416224 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11416224/
RECORD: Rec_0284123 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone
RECORD: Rec_0411212 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
sauvagine/corticotropin-releasing factor/urotensin I family
9606; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone sauvagine corticotropin-releasing factor urotensin I family
PaperPDB 3N93 structural record; X-ray; 2.50 A; chain C; residues 23-38
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