Peptide Database

Peptide NameVpr 29-43

Function Ontology

Antimicrobial

Antiviral

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Reverse transcriptase inhibition

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC85H128N26O19

DescriptionStandard

        EAVRHFPRIWLHSLG
    

Molecular Weight1818.09 Da

Isoelectric Point (pI)9.71

Net Charge (pH 7.0)1.01

Net Charge (pH 7.4) 0.74

Charge Density (pH 7.0) 0.0674

GRAVY Index-0.11

Hydrophobic Moment 0.75

Boman Index0.07

Instability Index31.30

Aliphatic Index 104.00

Aromaticity 0.1333

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 716.41

LogP -3.58

H-bond Donors 26.0

H-bond Acceptors 22.0

Rotatable Bonds 55.0

Heavy Atoms 130.0

Ring Count 6.0

Amide Bonds 14.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0257541 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman immunodeficiency virus 1 [Virus]

Tax ID11676

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Reverse transcriptase inhibition Integrase inhibition

MethodQualitative inhibition

RECORD: Rec_0369977 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral