Peptide Database

Peptide NameSLAY-screened peptide P3205

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC57H96N22O14S

DescriptionStandard

        FRSRHIGLTCR
    

Molecular Weight1345.58 Da

Isoelectric Point (pI)11.70

Net Charge (pH 7.0)2.84

Net Charge (pH 7.4) 2.57

Charge Density (pH 7.0) 0.2579

GRAVY Index-0.45

Hydrophobic Moment 0.20

Boman Index-0.35

Instability Index124.00

Aliphatic Index 70.91

Aromaticity 0.0909

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 609.16

LogP -6.73

H-bond Donors 25.0

H-bond Acceptors 19.0

Rotatable Bonds 44.0

Heavy Atoms 94.0

Ring Count 2.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057859 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/