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MYP_038767
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Basic Information
Omiganan
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Wound healing
Standard
12 amino acids
C90H126N26O13
Standard
Sequence
ILRWPWWPWRRK
Physicochemical Analysis
1780.13 Da
12.00
3.76
3.55
0.3133
-1.32
0.63
-0.26
131.93
65.00
0.3333
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
640.72
1.65
25.0
17.0
49.0
129.0
10.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0374934 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin analogue
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibacterial
Methicillin-resistant Staphylococcus aureus (MRSA)
2-8 μg/mL
MIC
PaperAntimicrobial and antifungal activities of a novel cationic antimicrobial peptide, omiganan, in experimental skin colonisation models PMID19524411 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19524411/
RECORD: Rec_0380104 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Wound healing
S. pneumoniae ATCC 49619
8 μg/mL
MIC
PaperRetro analog concept: comparative study on physico-chemical and biological properties of selected antimicrobial peptides.
RECORD: Rec_0383050 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 8927487 B2 Evidence URLhttps://patents.google.com/patent/US8927487B2/en PatentUS 8927487 B2
RECORD: Rec_0417322 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Wound healing
Enterococcus faecalis PCM 2673
16 μg/mL
MIC
PaperRetro analog concept: comparative study on physico-chemical and biological properties of selected antimicrobial peptides.
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