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MYP_038767
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Basic Information
Omiganan
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Wound healing
Standard
12 amino acids
C90H126N26O13
Standard
Sequence
ILRWPWWPWRRK
Physicochemical Analysis
1780.13 Da
12.00
3.76
3.55
0.3133
-1.32
0.63
-0.26
131.93
65.00
0.3333
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
640.72
1.65
25.0
17.0
49.0
129.0
10.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0212498 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Wound healing
C.glabrata ATCC 15126
128 μg/mL
MIC
PaperRetro analog concept: comparative study on physico-chemical and biological properties of selected antimicrobial peptides.
RECORD: Rec_0240079 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0250353 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
50 μM
MIC
PMID28105725 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28105725/
RECORD: Rec_0255896 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin analogue
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibacterial
Candida albicans
64 μg/mL
MIC
PaperAntimicrobial and antifungal activities of a novel cationic antimicrobial peptide, omiganan, in experimental skin colonisation models PMID19524411 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19524411/
RECORD: Rec_0271034 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin analogue
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibacterial
Serratia marcescens
128 μg/mL
MIC
PaperAntimicrobial and antifungal activities of a novel cationic antimicrobial peptide, omiganan, in experimental skin colonisation models PMID19524411 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19524411/
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