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MYP_038767
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Basic Information
Omiganan
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Wound healing
Standard
12 amino acids
C90H126N26O13
Standard
Sequence
ILRWPWWPWRRK
Physicochemical Analysis
1780.13 Da
12.00
3.76
3.55
0.3133
-1.32
0.63
-0.26
131.93
65.00
0.3333
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
640.72
1.65
25.0
17.0
49.0
129.0
10.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0148625 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Wound healing
Escherichia coli ATCC 25922 or 23506
16-32 μg/mL
MIC
PaperRetro analog concept: comparative study on physico-chemical and biological properties of selected antimicrobial peptides.
RECORD: Rec_0162345 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Hemolytic
human RBCs
250 μg/mL
IC50
PMID28453851 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28453851/
RECORD: Rec_0183357 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin analogue
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibacterial
Methicillin-resistant Staphylococcus epidermidis (MRSE)
4 μg/mL
MIC
PaperAntimicrobial and antifungal activities of a novel cationic antimicrobial peptide, omiganan, in experimental skin colonisation models PMID19524411 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19524411/
RECORD: Rec_0194086 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin analogue
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibacterial
Enterococcus faecalis
8-16 μg/mL
MIC
PaperAntimicrobial and antifungal activities of a novel cationic antimicrobial peptide, omiganan, in experimental skin colonisation models PMID19524411 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19524411/
RECORD: Rec_0208802 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Wound healing
A. niger ATCC 16404
64 μg/mL
MIC
PaperRetro analog concept: comparative study on physico-chemical and biological properties of selected antimicrobial peptides.
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