Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length516 amino acids

Chemical FormulaC2445H3811N693O735S17

DescriptionStandard

        MYREDCYGRGLVLHGDKTTTGASCISSMPNASNINLGIVRKGDKTTPCPKCGKPGTIANGEGKALYGGLPAAVDLCEVLCGCPPGSNKVIAPAGQWLGRGPSPEQQAWVKRDAEIAAAAAFWAAQEAIEQAKRSVPVFAKSCKRGAGNTEAGTSEEPHINFGRVGYYLPAPIDTTPPEPVQHAQAAKRKPSKAGKNSDDTLPWYQRIFGTKPDAPAQAGMPLTAPVATGAGAELAAAGWQGLRYAGGGFMTAGRWLVRTSPTGAAVIGMLPGTLNEGEPDMLAGSQLAALAGKSAPTRIRFQWVNDNYGRLKPVAYHIGADSGLDQVRVRSMKRNRFTGNYEFWADGADKPTIVWTPDEVEFKAPANTGNRDEPYLPSTITVLPLPSAGEVGSSSTSLPIPDEKSFDDYILVNLPHGMPPIYIYLSNDHKYHVAPKGNPPLQAFPDAQKAKKKTPVKGGGTLRSRWKDNSGKIYEWDSQHGTVEMYDRTGRKHLGEFDPITGEQTKPADPTRSVEK
    

Molecular Weight55218.72 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)8.26

Net Charge (pH 7.4) 7.33

Charge Density (pH 7.0) 0.0160

GRAVY Index-0.52

Hydrophobic Moment 0.65

Boman Index-0.01

Instability Index42.31

Aliphatic Index 65.16

Aromaticity 0.0775

Extinction Coeff. Reduced 85830.00

Extinction Coeff. Oxidized 86330.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0105502 VERIFIED: YES

Provenance & Taxonomy

OrganismRahnella sp. AA [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)