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MYP_038700
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Basic Information
Conopressin-S
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
9 amino acids
C41H74N16O11S2
Standard
Sequence
CIIRNCPRG
Physicochemical Analysis
1031.26 Da
9.02
1.74
1.51
0.1934
-0.06
0.77
-0.21
22.99
86.67
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
454.22
-5.23
18.0
15.0
32.0
70.0
1.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0141352 VERIFIED: YES
Provenance & Taxonomy
Conus striatus [Animal]
Conopressin-S
6493
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Hormone Endocrine Receptor modulation ACE inhibitory
V1b receptor
0.0083 μM
Ki
Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Conopressin-S (Conus striatus): PMID 18174156 PMID18174156 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18174156/
RECORD: Rec_0152935 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 11.1%, C 88.9% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Miscellaneous
PaperConoServer: updated content, knowledge, and discovery tools in the conopeptide database PMID22058133 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22058133/
RECORD: Rec_0156487 VERIFIED: YES
Provenance & Taxonomy
Conus striatus [Animal]
Conopressin-S
6493
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Hormone Endocrine Receptor modulation ACE inhibitory
Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Conopressin-S (Conus striatus): PMID 18174156 PMID18174156 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18174156/
RECORD: Rec_0181077 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0190019 VERIFIED: NO
Provenance & Taxonomy
Conus striatus [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Hormone
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