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MYP_038668
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Basic Information
Temporin-CEa
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C83H135N19O21
Standard
Sequence
FVDLKKIANIINSIF
Physicochemical Analysis
1735.07 Da
8.59
0.76
0.55
0.0506
0.95
0.74
0.33
17.29
156.00
0.1333
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
666.47
-2.95
22.0
22.0
59.0
123.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0193444 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
BEL-7402
36.9 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
RECORD: Rec_0204461 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
BCaP-37
39.42 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
RECORD: Rec_0214413 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HT-29
88.91 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
RECORD: Rec_0216757 VERIFIED: YES
Provenance & Taxonomy
Rana chensinensis [Animal]
Temporin
79015
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer Anti-inflammatory
X. arboricola pv. pruni and X. axonopodis pv. vesicatoria
3.1-6.2 μM
MIC
PaperMolecular Cloning of cDNAs Encoding Antimicrobial Peptide Precursors From the Skin of the Chinese Brown Frog, Rana Chensinensis
RECORD: Rec_0223149 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
LK-2
58.32 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
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