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MYP_038668
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Basic Information
Temporin-CEa
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C83H135N19O21
Standard
Sequence
FVDLKKIANIINSIF
Physicochemical Analysis
1735.07 Da
8.59
0.76
0.55
0.0506
0.95
0.74
0.33
17.29
156.00
0.1333
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
666.47
-2.95
22.0
22.0
59.0
123.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0382939 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HO-8910
64.75 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
RECORD: Rec_0384839 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
BGC-823
63.2 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
RECORD: Rec_0394870 VERIFIED: YES
Provenance & Taxonomy
Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0396911 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0401001 VERIFIED: YES
Provenance & Taxonomy
Rana chensinensis [Animal]
Chinese brown frog Rana chensinensis
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Bcap-37
40 μM
Cell viability assay
PMID23583573 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23583573/
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