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MYP_038668
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Basic Information
Temporin-CEa
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C83H135N19O21
Standard
Sequence
FVDLKKIANIINSIF
Physicochemical Analysis
1735.07 Da
8.59
0.76
0.55
0.0506
0.95
0.74
0.33
17.29
156.00
0.1333
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
666.47
-2.95
22.0
22.0
59.0
123.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0242609 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
12 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
RECORD: Rec_0244630 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
27.84 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
RECORD: Rec_0262764 VERIFIED: YES
Provenance & Taxonomy
Chinese brown [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID21871946 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21871946/
RECORD: Rec_0278597 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HO-8910
66.55 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
RECORD: Rec_0282670 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HO-8910
66.68 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
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