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MYP_038668
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Basic Information
Temporin-CEa
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C83H135N19O21
Standard
Sequence
FVDLKKIANIINSIF
Physicochemical Analysis
1735.07 Da
8.59
0.76
0.55
0.0506
0.95
0.74
0.33
17.29
156.00
0.1333
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
666.47
-2.95
22.0
22.0
59.0
123.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000420 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
BGC-823
61.63 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
RECORD: Rec_0003821 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
NCI-H446
65.29 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
RECORD: Rec_0005501 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
SMMC-7721
47.73 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
RECORD: Rec_0012421 VERIFIED: YES
Provenance & Taxonomy
Rana chensinensis [Animal]
Chinese brown frog Rana chensinensis
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
MDA-MB-231
40 μM
Cytotoxicity assay
PMID23577112;21871946 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23577112/
RECORD: Rec_0015871 VERIFIED: YES
Provenance & Taxonomy
skin of the Chinese brown frog,Rana chensinensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HeLa
43.87 μM
IC50
PaperPubMed PMID: 19341344 PMID19341344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19341344/
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