Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length185 amino acids

Chemical FormulaC926H1470N250O255S8

DescriptionStandard

        PETLPMAHEPMLLLAITELVANSAAFTYFTAGALRRNISSDTLPRQFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARQQPLVSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANMTGKPTITRNRLGGTVKLTGLVPNPELGTLPVPQVKHLETLLKFGLWLFGVPQANSKCCPRPVP
    

Molecular Weight20441.62 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)3.39

Net Charge (pH 7.4) 3.00

Charge Density (pH 7.0) 0.0183

GRAVY Index-0.03

Hydrophobic Moment 0.55

Boman Index0.10

Instability Index54.85

Aliphatic Index 94.38

Aromaticity 0.0703

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7921.44

LogP -91.27

H-bond Donors 268.0

H-bond Acceptors 271.0

Rotatable Bonds 645.0

Heavy Atoms 1439.0

Ring Count 41.0

Amide Bonds 201.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0262790 VERIFIED: NO

Provenance & Taxonomy

OrganismOriolus oriolus (Eurasian golden oriole) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria