Peptide Database

Peptide NameDermaseptin-DA3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC379H621N103O125S3

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSICEEKRENEDEEEQEDDEQSEEKRGMWSKIKNAGKAAAKASKKAAGKAALGAVSEALGEQ
    

Molecular Weight8716.80 Da

Isoelectric Point (pI)5.03

Net Charge (pH 7.0)-3.48

Net Charge (pH 7.4) -3.75

Charge Density (pH 7.0) -0.0435

GRAVY Index-0.53

Hydrophobic Moment 0.63

Boman Index-0.09

Instability Index52.25

Aliphatic Index 79.50

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3741.89

LogP -37.81

H-bond Donors 128.0

H-bond Acceptors 125.0

Rotatable Bonds 316.0

Heavy Atoms 610.0

Ring Count 5.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0298804 VERIFIED: NO

Provenance & Taxonomy

OrganismAgalychnis dacnicolor [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence