Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length476 amino acids

Chemical FormulaC2338H3703N605O680S19

DescriptionStandard

        MLPAVIALLMLLSCTSGQKPAIQVILTNKGLQYGKHTGTGLVQEKLENITLPDISGEINIKIGKVHYTLSGIAVKQCDLPEPSVQFFQDATGFKTSSSGLNVALAGEWRTRFGAIHDGGSFDMVMFGVDVTSVVELGKAPDGHLSITSISCDALVGDVNIHFHGGASFIFQPFVHYFKGRIRNEIESGICSAVHGSVDKLERHLQAMNVSFDVNEVLSLDLPLTDIPLIDASRLNLGLKGEFYSIRSHKEPPFKAQPFTMPEQPDYMLAVGLSDFTLNSASYGYYSDGLLQIVINDSMIPSISPIRLNTTSMGVFIPQLPKKFPGLLMSLQVYAREAPMFSFQPGAAKLSSQVDVKAFAIEPNGTQVPLFKLSVDSKFSTKLWISGGSLKGSVTMDNFTVTLAASEVGDFKTDALERSVRMAIKVVVLPKVNNKLGKGWILPRMKHAQLVNSVLKMEEGFLAVSSDVEVLLTDRFN
    

Molecular Weight51776.29 Da

Isoelectric Point (pI)6.42

Net Charge (pH 7.0)-2.53

Net Charge (pH 7.4) -3.47

Charge Density (pH 7.0) -0.0053

GRAVY Index0.12

Hydrophobic Moment 0.77

Boman Index0.15

Instability Index37.48

Aliphatic Index 98.26

Aromaticity 0.0819

Extinction Coeff. Reduced 29910.00

Extinction Coeff. Oxidized 30160.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0228427 VERIFIED: NO

Provenance & Taxonomy

OrganismAmphiprion ocellaris [Bacterium]

FamilyBPI

Tax ID80972

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence