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MYP_038602
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Basic Information
Dhvar4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C90H150N24O17
Standard
Sequence
KRLFKKLLFSLRKY
Physicochemical Analysis
1840.30 Da
11.22
5.76
5.54
0.4111
-0.42
0.72
-0.31
29.53
111.43
0.2143
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
709.96
-1.65
27.0
23.0
66.0
131.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0140143 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Evidence URLhttps://patents.google.com/patent/US20020111305A1/en PatentUS 2002/0111305 A1
RECORD: Rec_0154190 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antifungal
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/15196144/ PMID15196144 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15196144/
RECORD: Rec_0165071 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antileishmanial
Leishmania donovani MHOM/SD/00/1S-2D
1.5±0.1 μM
LC50; MTT assay
PMID18230684 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18230684/
RECORD: Rec_0170834 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Streptococcus mutans UA159
13.6 μM
MBC
PMID31207076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31207076/
RECORD: Rec_0189351 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
125 μg/mL
MIC
PMID10518718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10518718/
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