Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length142 amino acids

Chemical FormulaC701H1120N208O216S13

DescriptionStandard

        MHFSSQLRRFMVDGGTDFFWNLEDGQWMTIAGRSDTPLEDQSTNQELRVDRREQLSQCKRNSCPNTARPRKCFSNITGYCRKKCEMGEIYEVACRNGKLCCVNEGENKKHKKAPKSPSFLVQSDGKMDYVILPTTTLLTIQI
    

Molecular Weight16334.50 Da

Isoelectric Point (pI)8.81

Net Charge (pH 7.0)4.62

Net Charge (pH 7.4) 4.14

Charge Density (pH 7.0) 0.0325

GRAVY Index-0.74

Hydrophobic Moment 0.58

Boman Index-0.19

Instability Index62.48

Aliphatic Index 59.01

Aromaticity 0.0775

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6958.57

LogP -79.13

H-bond Donors 249.0

H-bond Acceptors 236.0

Rotatable Bonds 555.0

Heavy Atoms 1138.0

Ring Count 21.0

Amide Bonds 157.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0220498 VERIFIED: NO

Provenance & Taxonomy

OrganismAcinonyx jubatus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin