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MYP_038550
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Basic Information
Guanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Enzyme / Catalytic activity ▸ Hydrolase
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
633 amino acids
C3209H5096N878O972S28
Standard
Sequence
MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNLADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF
Physicochemical Analysis
72425.91 Da
5.98
-9.06
-10.44
-0.0143
-0.51
0.73
-0.07
39.03
82.42
0.0758
57870.00
58370.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0089077 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Mycobacterium bovis (Gram-positive)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID14702039;17974005;16710414;15489334 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14702039/
RECORD: Rec_0242000 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Toxoplasma gondii
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID14702039;17974005;16710414;15489334 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14702039/
RECORD: Rec_0275615 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Listeria monocytogenes (Gram-positive)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID14702039;17974005;16710414;15489334 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14702039/