Peptide Database

Peptide Namedefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC465H748N132O134S9

DescriptionStandard

        MVKVYFLVALLFVAVAAIMAVPVEEEYEPLEHAGIEERADRQRRVTCDLLSIKGVAEHSACAANCLSMGKAGGRCENGVCLCRKTNFKDLWDKRFG
    

Molecular Weight10620.30 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.36

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0038

GRAVY Index0.09

Hydrophobic Moment 0.49

Boman Index0.04

Instability Index39.82

Aliphatic Index 91.46

Aromaticity 0.0729

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4271.68

LogP -37.47

H-bond Donors 155.0

H-bond Acceptors 145.0

Rotatable Bonds 357.0

Heavy Atoms 740.0

Ring Count 12.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0249152 VERIFIED: NO

Provenance & Taxonomy

OrganismBombus bifarius [Animal]

FamilyDefensin

Tax ID103933

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal