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MYP_038472
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
7 amino acids
C40H65N11O11
Standard
Sequence
KKYNVPQ
Physicochemical Analysis
876.01 Da
9.70
1.76
1.55
0.2510
-1.93
0.13
-0.45
63.60
41.43
0.1429
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
387.58
-3.18
12.0
13.0
28.0
62.0
2.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0058284 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
ACE-inhibitory peptide
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperAngiotensin-converting enzyme-inhibitory peptides in Manchego cheeses manufactured with different starter cultures
RECORD: Rec_0135640 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0199291 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
alpha-S1-Casein-derived
9940
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
716.9 μM
IC50
PaperAngiotensin converting enzyme-inhibitory activity of peptides isolated from Manchego cheese Stability under simulated gastrointestinal digestion | Gomez-Ruiz, JA. et al. | DOI: 10.1016/j.idairyj.2004.04.007 Evidence URLhttps://www.uniprot.org/uniprotkb/P04653/entry
RECORD: Rec_0250830 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Casein-derived peptide
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
75.9 ± 1.7 μM
IC50
RECORD: Rec_0357206 VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
PaperAngiotensin-converting enzyme-inhibitory peptides in Manchego cheeses manufactured with different starter cultures