Peptide Database

Peptide NameAlpha-like toxin CsEv5

Function Ontology

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC259H410N74O89S10

DescriptionStandard

        KDGYPVDSKGCKLSCVANNYCDNQCKMKKASGGHCYAMSCYCEGLPENAKVSDSATNIC
    

Molecular Weight6305.12 Da

Isoelectric Point (pI)7.68

Net Charge (pH 7.0)0.77

Net Charge (pH 7.4) 0.37

Charge Density (pH 7.0) 0.0130

GRAVY Index-0.52

Hydrophobic Moment 0.43

Boman Index-0.08

Instability Index54.08

Aliphatic Index 43.05

Aromaticity 0.0678

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2649.23

LogP -35.90

H-bond Donors 97.0

H-bond Acceptors 101.0

Rotatable Bonds 210.0

Heavy Atoms 432.0

Ring Count 7.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0105372 VERIFIED: YES

Provenance & Taxonomy

OrganismCentruroides sculpturatus [Animal]

FamilySodium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide11-59; 15-35; 21-40; 25-42

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense