Peptide Database

Peptide NameDepatuxizumab

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length446 amino acids

Chemical FormulaC2186H3391N577O667S14

DescriptionStandard

        QVQLQESGPGLVKPSQTLSLTCTVSGYSISSDFAWNWIRQPPGKGLEWMGYISYSGNTRYQPSLKSRITISRDTSKNQFFLKLNSVTAADTATYYCVTAGRGFPYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    

Molecular Weight48875.69 Da

Isoelectric Point (pI)8.85

Net Charge (pH 7.0)9.46

Net Charge (pH 7.4) 8.52

Charge Density (pH 7.0) 0.0212

GRAVY Index-0.40

Hydrophobic Moment 0.54

Boman Index0.02

Instability Index40.28

Aliphatic Index 70.70

Aromaticity 0.0942

Extinction Coeff. Reduced 77810.00

Extinction Coeff. Oxidized 78435.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0048255 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

FamilyMonoclonal antibody

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Diagnostic

RECORD: Rec_0286516 VERIFIED: NO