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MYP_038408
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Basic Information
Lacticin Q
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
53 amino acids
C279H445N71O67S
Standard
Sequence
MAGFLKVVQLLAKYGSKAVQWAWANKGKILDWLNAGQAIDWVVSKIKQILGIK
Physicochemical Analysis
5898.02 Da
10.10
5.49
5.26
0.1037
0.30
0.60
0.22
7.37
121.51
0.1132
23490.00
23490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2241.67
-11.69
77.0
74.0
201.0
418.0
10.0
58.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0116284 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis QU5 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Enterococcus faecium BFE900
16 μM
MIC
PMID26771761 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26771761/
RECORD: Rec_0116498 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis QU5 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Carnobacterium maltaromaticum UAL26
1 μM
MIC
PMID26771761 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26771761/
RECORD: Rec_0118533 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]; Bacteria [Bacterium]
Bacteriocin
1358; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID23844357 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23844357/
RECORD: Rec_0125658 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis QU 5 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Pediococcus pentosaceus JCM 5885
0.31 μM
MIC
PMID17351096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17351096/
RECORD: Rec_0141210 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Bacteriocin
1358
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
APD prediction and calculation: mol weight: 5898.083; Mol formula: C279H451N69O67S1. Sequence alignment revealed its similarity (49%) to Aureocin A53 (AP1131). leaderless. Chemical modification: The N-terminal methionine of lacticin Q is formylated. Bacteriocins that lack leader or signal sequences are expected to have N-formylmethionine at their N termini
Bio-Activity Profile
Antimicrobial
B. circulans JCM 2504T, Enterococcus faecalis JCM 5803T or JCM 5804T, E. mundtii QU 2, L. alimentarius JCM 1095T, L. sakei JCM 1157T, L. mesenteroides JCM 6124T, L. innocua ATCC 33090T
33-70 μM
MIC
PaperStructural analysis and characterization of lacticin Q, a novel bacteriocin belonging to a new family of unmodified bacteriocins of gram-positive bacteria.
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