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MYP_038396
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Basic Information
Protegrin 1 / Neutrophil peptide 1 (5-16)[C2T][C11T]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
12 amino acids
C66H109N21O16S2
Standard
Sequence
LTYCRRRFCVTV
Physicochemical Analysis
1516.83 Da
9.69
2.74
2.51
0.2283
0.32
0.25
-0.20
91.28
80.83
0.1667
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
629.81
-5.31
27.0
21.0
47.0
105.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0035802 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Neisseria gonorrhoeae F62
0.45
MIC
PMID9009324 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9009324/
RECORD: Rec_0054571 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
80 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/18455267/ PMID18455267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18455267/
RECORD: Rec_0093640 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
0.5 μg/mL
MIC
PMID15629531 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15629531/
RECORD: Rec_0110250 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Neisseria gonorrhoeae FA19
1.37
MIC
PMID9009324 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9009324/
RECORD: Rec_0177986 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
2.7 μg/mL
MIC
PMID15629531 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15629531/
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