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MYP_038393
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Basic Information
Anticancerous peptide 1 (Cr-ACP1; Plants)
Anticancer
Anticancer ▸ Apoptosis induction
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C50H71N11O14
Standard
Sequence
AWKLFDDGV
Physicochemical Analysis
1050.16 Da
4.21
-1.20
-1.39
-0.1337
0.04
0.62
0.22
13.17
86.67
0.2222
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
412.53
-1.32
14.0
13.0
32.0
75.0
3.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0324554 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0328167 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
PaperIdentification and characterization of a bactericidal and proapoptotic peptide from Cycas revoluta seeds with DNA binding properties
RECORD: Rec_0333294 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
Bacillus subtilis
30 μM
MIC
PMID21882228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21882228/
RECORD: Rec_0344569 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Plant]
Anticancerous peptide 1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Cytotoxic
Human colon adenocarcinoma HCT-15
1000 μM
IC50
PMID21882228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21882228/
RECORD: Rec_0368065 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
PMID21882228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21882228/
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