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MYP_038393
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Basic Information
Anticancerous peptide 1 (Cr-ACP1; Plants)
Anticancer
Anticancer ▸ Apoptosis induction
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C50H71N11O14
Standard
Sequence
AWKLFDDGV
Physicochemical Analysis
1050.16 Da
4.21
-1.20
-1.39
-0.1337
0.04
0.62
0.22
13.17
86.67
0.2222
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
412.53
-1.32
14.0
13.0
32.0
75.0
3.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0232955 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Plant]
Anticancerous peptide 1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Cytotoxic Anti-Gram-positive
Bacillus subtilis
30 μM
MIC
PMID21882228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21882228/
RECORD: Rec_0244637 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0260493 VERIFIED: NO
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0305266 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Plant]
Anticancerous peptide 1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Cytotoxic
Human epidermoid cancer Hep2
1500 μM
IC50
PMID21882228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21882228/
RECORD: Rec_0308574 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Cytotoxic
duced a cell viability of 66% at the concentration of 4 mM
4000 μM
Cytotoxicity
PMID21882228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21882228/
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