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MYP_038393
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Basic Information
Anticancerous peptide 1 (Cr-ACP1; Plants)
Anticancer
Anticancer ▸ Apoptosis induction
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C50H71N11O14
Standard
Sequence
AWKLFDDGV
Physicochemical Analysis
1050.16 Da
4.21
-1.20
-1.39
-0.1337
0.04
0.62
0.22
13.17
86.67
0.2222
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
412.53
-1.32
14.0
13.0
32.0
75.0
3.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0140067 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Cytotoxic
mM in Hep2 (Human epidermoid cancer cells)
PMID21882228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21882228/
RECORD: Rec_0142394 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
EEscherichia coli strain ATCC 8739
30 μM
MIC
PMID21882228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21882228/
RECORD: Rec_0160185 VERIFIED: YES
Provenance & Taxonomy
Cycas revoluta [Plant]
Seeds,Cycas revoluta
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial
PMID21882228;18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21882228/
RECORD: Rec_0166723 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Anti-Gram-positive Anti-Gram-negative
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0195338 VERIFIED: NO
Provenance & Taxonomy
Cycas revoluta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Anticancer Hemolytic Non-ribosomal
Qualitative functional evidence
PMID21882228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21882228/; https://www.uniprot.org/uniprotkb/B3EWE7/entry; https://bblserver.org.in/ampdb/
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