Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length646 amino acids

Chemical FormulaC3061H4919N851O950S12

DescriptionStandard

        MPGPASYQNGFPYNANGEIRILITGGPTPPSGTIPASPPSNGGLYVSMLPPNVAPVYLKDRVSVEYVPGKGRQFTPYGQLAQLEKIFDDQIAAARNRIAEPVDRIIDRVNAVFRLVNTHVGNDPRVISSEKLLREANHGLQVANSEVQLSEGNVSQKHEAAEKALNDVKPKLGLSGVEPEDYDALLTRALEPVSRSYWEEYSVKPRVEEFNAKQRLLAALDNIAVVIQDVESKASTLTDVVNQVNKERADAETKAKAEEEAKAKAETEARAKTAELMTKAGVKPTPVYTPEMVKSAQASLAAVGAMVLNRAPGMLQLSTAAEGVLTTTSELAGSIAGAVWRGAIALAEAATVSTAGATVSALVMGFWPTKAGEGSDKLYGRDIVMFGFQANLIAAGKVSISPEMHSVDLPVRGSLVMENGQQQVKLVKTGIGGVPASVSILKAVRDEKTGLDRITLPAVGGAPSRTILVNPAPVGPTAPPHTGNSSPAPVTPVHTGTTVKQADSIVTTSFPADDLKELQDFIYWQPDATGSGVEPIYVMLSDPLDSGRFTRKQLDKKFKHAIDFGISDTKKNSETLTKFRDEVNAHLADKETVERGTYRREKGSKVYFNPKSMRVVILKANGDFLSGWKINPDADNGRIYLETGDL
    

Molecular Weight69226.71 Da

Isoelectric Point (pI)6.33

Net Charge (pH 7.0)-2.70

Net Charge (pH 7.4) -3.51

Charge Density (pH 7.0) -0.0042

GRAVY Index-0.28

Hydrophobic Moment 0.91

Boman Index0.02

Instability Index28.38

Aliphatic Index 85.62

Aromaticity 0.0573

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51340.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0227048 VERIFIED: YES

Provenance & Taxonomy

OrganismSerratia plymuthica [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)