Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length426 amino acids

Chemical FormulaC2134H3337N551O619S10

DescriptionStandard

        IKINAFSLPNTSLAFVPGVGIRALTNHGTTNVSLDWEVRAPLFHDAGGADLFLSGVYFTGVLLPTQNVFGHPALRLQDCSAQVSHAHVSFSGELSALYNTFAEPMEKPILKNLNTMLCPIITDEVEALNVNLSSLDVLTKIDNFTLLDYSLVGPPEITEHYLDLNLKGVFYPLDNLADPPFSPEPFELPERLDSMVYIGISEYFFQSASFAHFAAGAFSITLSTKEISNHFIQNSQGIGIVLSRLADLYILSQPLMLRIMATEPPVVRLQPGNFTLDIPASVIVLTQFKNSTEVEPIVSMDFVASTSVGLAILGQRLVCSLSLNRFRLSGSEANRSDIKVLRFENILSSILHFGVLPLANTKLQQGFPLPRPYNVSLVNSDIEVLEGFILISTNLKYEMSSKQQPSFHGWGDLNRIRRQGTRQPAP
    

Molecular Weight46936.29 Da

Isoelectric Point (pI)5.38

Net Charge (pH 7.0)-10.34

Net Charge (pH 7.4) -11.17

Charge Density (pH 7.0) -0.0243

GRAVY Index0.15

Hydrophobic Moment 0.76

Boman Index0.16

Instability Index37.61

Aliphatic Index 105.26

Aromaticity 0.0915

Extinction Coeff. Reduced 25900.00

Extinction Coeff. Oxidized 26025.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076608 VERIFIED: NO

Provenance & Taxonomy

OrganismChinchilla lanigera (Long-tailed chinchilla) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria