Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC335H530N80O91S11

DescriptionStandard

        MKPLLIMLVFLSLWDPVLAGINSLPSEMHKKCYKNGICRLECYESEMLVAYCMFQLECCVTGNPAP
    

Molecular Weight7486.99 Da

Isoelectric Point (pI)5.62

Net Charge (pH 7.0)-1.46

Net Charge (pH 7.4) -1.84

Charge Density (pH 7.0) -0.0222

GRAVY Index0.42

Hydrophobic Moment 0.53

Boman Index0.22

Instability Index54.73

Aliphatic Index 98.94

Aromaticity 0.0909

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2679.32

LogP -16.20

H-bond Donors 95.0

H-bond Acceptors 102.0

Rotatable Bonds 242.0

Heavy Atoms 517.0

Ring Count 13.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0360309 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence