Peptide Database

Peptide NameIL-33

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length159 amino acids

Chemical FormulaC799H1234N200O258S7

DescriptionStandard

        SITGISPITEYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGKMLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFIGVKDNHLALIKVDSSENLCTENILFKLSET
    

Molecular Weight17993.99 Da

Isoelectric Point (pI)4.80

Net Charge (pH 7.0)-12.93

Net Charge (pH 7.4) -13.62

Charge Density (pH 7.0) -0.0813

GRAVY Index-0.42

Hydrophobic Moment 0.49

Boman Index0.01

Instability Index45.60

Aliphatic Index 82.70

Aromaticity 0.0881

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14690.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7360.75

LogP -72.07

H-bond Donors 251.0

H-bond Acceptors 259.0

Rotatable Bonds 604.0

Heavy Atoms 1264.0

Ring Count 28.0

Amide Bonds 170.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0136491 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Immunomodulatory Signaling peptide

TargetInterleukin-33 receptor (Human)