Peptide Database

Peptide NameCathelicidin-3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length182 amino acids

Chemical FormulaC897H1436N246O279S7

DescriptionStandard

        METQRASLSLGRWSLWLLLLGLALPSASAQALSYREAVLRAVDQLNEKSSEANLYRLLELDPPPKEDDENPNIPKPVSFRVKETVCPRTSQQPAEQCDFKENGLVKQCVGTVTLDAVKGKINITCEEVEDPGARKPVSFRVKETVCPRLSLQPPEQCDFKENGVLKEYGVTVTVDHWNDVFT
    

Molecular Weight20354.93 Da

Isoelectric Point (pI)5.08

Net Charge (pH 7.0)-5.43

Net Charge (pH 7.4) -5.84

Charge Density (pH 7.0) -0.0298

GRAVY Index-0.43

Hydrophobic Moment 0.67

Boman Index-0.07

Instability Index33.14

Aliphatic Index 86.15

Aromaticity 0.0604

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8460.03

LogP -98.35

H-bond Donors 290.0

H-bond Acceptors 282.0

Rotatable Bonds 672.0

Heavy Atoms 1429.0

Ring Count 29.0

Amide Bonds 198.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0378001 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal