Peptide Database

Peptide NameEndoribonuclease ZC3H12A

Function Ontology

Antiviral

Antiviral ▸ Anti-Flavivirus ▸ Anti-Dengue virus

Antiviral ▸ Anti-Flavivirus ▸ Anti-Japanese encephalitis virus

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length599 amino acids

Chemical FormulaC2910H4531N817O881S20

DescriptionStandard

        MSGPCGEKPVLEASPTMSLWEFEDSHSRQGTPRPGQELAAEEASALELQMKVDFFRKLGYSSTEIHSVLQKLGVQADTNTVLGELVKHGTATERERQTSPDPCPQLPLVPRGGGTPKAPNLEPPLPEEEKEGSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAYESDGIVVSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLTLEHRKQPCPYGRKCTYGIKCRFFHPERPSCPQRSVADELRANALLSPPRAPSKDKNGRRPSPSSQSSSLLTESEQCSLDGKKLGAQASPGSRQEGLTQTYAPSGRSLAPSGGSGSSFGPTDWLPQTLDSLPYVSQDCLDSGIGSLESQMSELWGVRGGGPGEPGPPRAPYTGYSPYGSELPATAAFSAFGRAMGAGHFSVPADYPPAPPAFPPREYWSEPYPLPPPTSVLQEPPVQSPGAGRSPWGRAGSLAKEQASVYTKLCGVFPPHLVEAVMGRFPQLLDPQQLAAEILSYKSQHPSE
    

Molecular Weight65698.35 Da

Isoelectric Point (pI)6.50

Net Charge (pH 7.0)-2.45

Net Charge (pH 7.4) -3.60

Charge Density (pH 7.0) -0.0041

GRAVY Index-0.60

Hydrophobic Moment 0.64

Boman Index-0.06

Instability Index64.10

Aliphatic Index 66.26

Aromaticity 0.0768

Extinction Coeff. Reduced 69330.00

Extinction Coeff. Oxidized 69955.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0324156 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyZC3H12

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Ser99, Ser344, Ser438, Ser442

Bio-Activity Profile

Function

Antiviral Anti-HIV-1

TargetHuman immunodeficiency virus type 1(HIV-1)

RECORD: Rec_0373401 VERIFIED: YES