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MYP_038231
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Basic Information
AMP-020
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
16 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GLXDVIKKVASVIGGL
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0169261 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
ambiguous or noncanonical residue-containing peptide [Modified]
1-Nap: 1-Naphyl at 3; 1-Nap: 1-Naphyl
Bio-Activity Profile
Hemolytic
human red blood cells
>32 μg/mL
HC50
PMID31336137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31336137/
RECORD: Rec_0243635 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
ambiguous or noncanonical residue-containing peptide [Modified]
1-Nap: 1-Naphyl at 3; 1-Nap: 1-Naphyl
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 90028
32 μg/mL
MIC
PMID31336137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31336137/
RECORD: Rec_0256932 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
ambiguous or noncanonical residue-containing peptide [Modified]
Biphenylalanine at 3; Biphenylalanine
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Cryptococcus neoformans var. grubii H99 ATCC 20887
>32 μg/mL
MIC
PMID31336137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31336137/
RECORD: Rec_0299705 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
ambiguous or noncanonical residue-containing peptide [Modified]
Biphenylalanine at 3; Biphenylalanine
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
32 μg/mL
MIC
PMID31336137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31336137/
RECORD: Rec_0318254 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
ambiguous or noncanonical residue-containing peptide [Modified]
Biphenylalanine at 3; Biphenylalanine
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus JE2 MRSA
8 μg/mL
MIC
PMID31336137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31336137/
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