Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC332H524N82O89S10

DescriptionStandard

        MKPLLIVLVLLFFWDPVVAGLNPLASEMHRKCYGNGICRLECSTSEMLVAYCMFQLECCVKGNPDP
    

Molecular Weight7408.86 Da

Isoelectric Point (pI)5.59

Net Charge (pH 7.0)-1.46

Net Charge (pH 7.4) -1.83

Charge Density (pH 7.0) -0.0222

GRAVY Index0.51

Hydrophobic Moment 0.54

Boman Index0.23

Instability Index30.80

Aliphatic Index 101.82

Aromaticity 0.0909

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2674.74

LogP -17.01

H-bond Donors 95.0

H-bond Acceptors 99.0

Rotatable Bonds 237.0

Heavy Atoms 513.0

Ring Count 13.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0190546 VERIFIED: NO

Provenance & Taxonomy

OrganismLeptonychotes weddellii (Weddell seal) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0378690 VERIFIED: NO

Provenance & Taxonomy

OrganismNeomonachus schauinslandi [Animal]

FamilyDefensin

Tax ID29088

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence