Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length512 amino acids

Chemical FormulaC2448H3790N694O751S17

DescriptionStandard

        MASVNRGCTVHGKNVGLHGDKTSTGAQCIAARPGMSVMGKLKLYIGDKTTPCPKCGEVGVIITGDHRQTNGEAVAVDGSVIHCDCPMGSNFLIAPGTVQVNDPFGVLEPPVNKAAAAAAAALSALPVFAKSCLRGEGCTDAGTDQESVDNFGHAGYYCATPQAEQPEEEPVQHAQAAKKHKPAEPTPPPEDNRPWYKRLFSSPDTTKAAVTAGTATARAATTAGITTGATTEAGYATLQKIGGNLTAAGRWITPNPSTVFLFGMFYSPKLNSDEQDYIDRMRLEQAAQKKEDVPTRVRFRWEADQYGTMRPKGFHVSARGGRDKVPVRMLQKNTTTGNYEFWEDGATKPIIVWTPDDPGYASPSNTGKQDNVYIPPNVLVYPESEIDSPWSTETPAPGERSFRDYILVHPAGIFDPVYIYLNAAHKYHTPPKENPPLPAFPDAKKAQAKTPVKGGGKLRNRWKDSEGKIYEWDSQHGTVEVYDRSGRNHLGEFNHITGEQTKPANPTRKVEK
    

Molecular Weight55503.59 Da

Isoelectric Point (pI)7.60

Net Charge (pH 7.0)1.69

Net Charge (pH 7.4) 0.49

Charge Density (pH 7.0) 0.0033

GRAVY Index-0.62

Hydrophobic Moment 0.63

Boman Index-0.04

Instability Index41.09

Aliphatic Index 59.51

Aromaticity 0.0801

Extinction Coeff. Reduced 70820.00

Extinction Coeff. Oxidized 71320.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0268639 VERIFIED: YES

Provenance & Taxonomy

OrganismRaoultella sp. Lac1 [Bacterium]

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli