Peptide Database

Peptide NameCrustacean hyperglycemic hormone

Function Ontology

Developmental biology ▸ Molting regulation

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC371H579N99O112S6

DescriptionStandard

        QVFDQACKGIYDRAIFKKLDRVCEDCYNLYRKPYVATTCRQNCYANSVFRQCLDDLLLIDVVDEYISGVQTV
    

Molecular Weight8410.55 Da

Isoelectric Point (pI)5.12

Net Charge (pH 7.0)-1.29

Net Charge (pH 7.4) -1.61

Charge Density (pH 7.0) -0.0180

GRAVY Index-0.14

Hydrophobic Moment 0.80

Boman Index-0.05

Instability Index19.26

Aliphatic Index 91.94

Aromaticity 0.1250

Extinction Coeff. Reduced 8940.00

Extinction Coeff. Oxidized 9315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3474.46

LogP -31.19

H-bond Donors 126.0

H-bond Acceptors 117.0

Rotatable Bonds 278.0

Heavy Atoms 588.0

Ring Count 10.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0095960 VERIFIED: YES

Provenance & Taxonomy

OrganismProcambarus bouvieri [Animal]

FamilyCrustacean hyperglycemic hormone

Tax ID6729

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

ChiralityD-residue-containing modified peptide [Mixed]

N-TermPyroglutamate

C-TermAmidation

Disulfide7-43; 23-39; 26-52

Other Mods3:D-phenylalanine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Molting regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0217053 VERIFIED: YES

Provenance & Taxonomy

OrganismProcambarus clarkii [Animal]

FamilyArthropod CHH/MIH/GIH/VIH hormone

Tax ID6728

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Other ModsPhe3 D-phenylalanine, in form CHH-II

Bio-Activity Profile

Function

Neuropeptide Arthropod neurohormone

RECORD: Rec_0358136 VERIFIED: YES

Provenance & Taxonomy

OrganismProcambarus clarkii [Animal]

FamilyCrustacean hyperglycemic hormone

Tax ID6728

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

ChiralityD-residue-containing modified peptide [Mixed]

N-TermPyroglutamate

C-TermAmidation

Disulfide7-43; 23-39; 26-52

Other Mods3:D-phenylalanine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Molting regulator

Targetthe sinus gland

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0427329 VERIFIED: YES

Provenance & Taxonomy

OrganismProcambarus clarkii [Animal]

FamilyCrustacean hyperglycemic hormone

Tax ID6728

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

ChiralityD-residue-containing modified peptide [Mixed]

N-TermPyroglutamate

C-TermAmidation

Disulfide7-43; 23-39; 26-52

Other Mods3:D-phenylalanine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Molting regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour