Peptide Database

Peptide NameP _prot

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC67H116N20O22S2

DescriptionStandard

        KYTGKCTKSKNECK
    

Molecular Weight1617.89 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.49

Charge Density (pH 7.0) 0.2669

GRAVY Index-1.81

Hydrophobic Moment 0.24

Boman Index-0.57

Instability Index45.76

Aliphatic Index 0.00

Aromaticity 0.0714

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 733.03

LogP -9.72

H-bond Donors 28.0

H-bond Acceptors 28.0

Rotatable Bonds 59.0

Heavy Atoms 111.0

Ring Count 1.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0353226 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsReduced cysteine thiol state

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans CBS 5982

Activity10 μM

MethodMIC

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