Peptide Database

Peptide NameT-206

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC176H283N53O57

DescriptionStandard

        ISIELNKAKSDLEESKEWIRRSNQKLDSIGNWHQ
    

Molecular Weight4053.45 Da

Isoelectric Point (pI)6.78

Net Charge (pH 7.0)-0.14

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0042

GRAVY Index-1.21

Hydrophobic Moment 0.66

Boman Index-0.29

Instability Index72.56

Aliphatic Index 83.24

Aromaticity 0.0588

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1852.16

LogP -19.65

H-bond Donors 64.0

H-bond Acceptors 58.0

Rotatable Bonds 144.0

Heavy Atoms 286.0

Ring Count 5.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0114917 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman parainfluenza virus 3 [Virus]

FamilyVirus-derived peptide

Tax ID11216;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

TargetHuman parainfluenza virus type 3 (Fusion); Vero

MethodImmunoprecipitation

PaperMethods for the inhibition of respiratory syncytial virus transmission | Dani Paul Bolognesi, Thomas James Matthews, Carl T. Wild, Shawn O'Lin Barney,Dennis Michael Lambert, Stephen Robert Petteway | Trimeris, Inc., Durham NC | Patent:US6440656 Evidence URLhttps://patents.google.com/patent/US6440656/en PatentUS6440656

RECORD: Rec_0388185 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 67.6%, E 0.0%, T 20.6%, C 11.8% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial