Peptide Database

Peptide Name[N Psi P]BN(6-14) [Bombesin antagonist]

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Growth inhibitors

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC43H64N12O14

DescriptionStandard

        DNALQWAVG
    

Molecular Weight973.04 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.1376

GRAVY Index-0.02

Hydrophobic Moment 0.30

Boman Index0.24

Instability Index18.98

Aliphatic Index 97.78

Aromaticity 0.1111

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 435.39

LogP -4.01

H-bond Donors 14.0

H-bond Acceptors 13.0

Rotatable Bonds 29.0

Heavy Atoms 69.0

Ring Count 2.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0045959 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyBombesin

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermAmidation

Other ModsD-Nal =Napthylalanine

Bio-Activity Profile

Function

Growth inhibitors

Activity0.005 μM

MethodIC50

Half-LifeSCLC cell line NCI-H345, in vitro; 11820 s